Would you like
to...? (pick any one or more)
Is your current yield < 85%?
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Does your current process and/or reaction take 8 hours or
longer and you desire higher throughput?
Would you like to eliminate or consolidate unit
operations, especially those involving intermediate isolation?
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Are you using methoxide (methylate), ethoxide,
t-butoxide, NaH, NaNH2 (even LDA in rare cases)?
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Do you want easier workup, better phase separation,
better solvent recovery or lower emissions?
Are you using DMSO, NMP, DMF, DMAc, HMPA, methylene
dichloride, ethylene dichloride, acetone, etc.?
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Are you using 15 mole% excess or higher of any raw
material, including but not limited to cyanide, phosgene, borohydride,
benzoyl chloride (or hundreds of others)?
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Does solvent take up more than 50% of your reactor
volume?
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Does your product purity suffer from high levels of
by-products, especially hydrolysis products?
Are you using water-sensitive reactants or products?
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